Description
Studies referenced in this video:
0:34 Miller (2023, 2025): dramatic global increases in heart conditions over recent decades
https://pubmed.ncbi.nlm.nih.gov/36446151 and https://pubmed.ncbi.nlm.nih.gov/39228044
1:38 Anaya et al. (2016): “heart ecology” — environment, more than genetics, shapes the immune system
https://pubmed.ncbi.nlm.nih.gov/27199979
2:05 Pathogen burden: the cumulative effects of multiple persistent pathogens on morbidity and mortality
https://pmc.ncbi.nlm.nih.gov/articles/PMC6175667/
2:52 Infectious burden: a new risk factor and treatment target for atherosclerosis
https://pmc.ncbi.nlm.nih.gov/articles/PMC2891124/
5:54 Salugenesis — Robert K. Naviaux
https://www.sciencedirect.com/science/article/pii/S1567724923000351
6:40 Metabolic Vulnerability Index and Atherosclerosis Incident: A Prospective Cohort Study From the UK Biobank
https://pubmed.ncbi.nlm.nih.gov/41220154/
8:15 MVX and type 2 diabetes outcomes and diabetes-related mortality
https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.70789
9:14 The Metabolic Vulnerability Index (MVX) in Subclinical Thyroid Disorders and Euthyroidism: A Cross-Sectional Exploratory Analysis from the ELSA-Brasil Study
https://pmc.ncbi.nlm.nih.gov/articles/PMC12471407/
9:31 Associations of Multimarkers of Metabolic Malnutrition and Inflammation With All-Cause Mortality and Their Interplay With Thyroid Function
https://pmc.ncbi.nlm.nih.gov/articles/PMC12880609/
11:02 Metabolic vulnerability index increased risk of all-cause mortality among individuals with stage 4 cardiovascular-renal-metabolic syndrome: a prospective cohort study in UK Biobank
https://link.springer.com/article/10.1186/s12872-026-06225-6
11:46 Metabolic vulnerability index and Life’s Essential 8 with risk of major adverse cardiovascular events
https://www.nature.com/articles/s44325-026-00139-0
15:42 Associations of Metabolic Vulnerability Index with Cardiometabolic Diseases, Multimorbidity, and All-cause Mortality
https://www.medrxiv.org/content/10.64898/2026.02.09.26345939v1.full
16:28 Associations of Multimarkers of Metabolic Malnutrition and Inflammation with All-Cause Mortality by Multimorbidity Status
https://pubmed.ncbi.nlm.nih.gov/40507016/
17:41 Betaine supplementation (20 g a day for 12 months) and MVX
https://pubmed.ncbi.nlm.nih.gov/40758380/
18:30 Carnivore diet vs. Standard American Diet: mean MVX 37 vs. 52 (unpublished)
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00:00 - Introduction & The Exposome Framework
02:00 - Total Pathogen Burden & Chronic Illness
03:33 - Why Routine Labs Miss Chronic Infection Load
05:25 - Holobiome & Salutogenesis: The Healing Cycle
06:34 - MVX Plus vs. Standard Cardiovascular Markers
08:15 - MVX Plus vs. Type 2 Diabetes Screening
09:13 - MVX Plus vs. Standard Thyroid Panels
11:02 - Cardiovascular-Renal-Metabolic Syndrome
11:46 - Predicting MACE (Major Adverse Cardiac Events)
13:38 - An Actionable, Dynamic Health Metric
15:41 - Cardiometabolic Disease & Mortality Risk
16:28 - MVX vs. Direct Nutrient Testing
17:41 - Clinical Intervention: Betaine & Fatty Liver
18:30 - Diet Study: Carnivore vs. Standard American Diet
19:32 - How to Get Tested & Practitioner Resources