Urine-based Testing to Detect HPV - Editors in Conversation

ASM - Microbes Make Our World Podcast 7 days ago

Description

Is the future of cervical cancer screening non-invasive? In this episode of Editors in Conversation, hosts Ellie Theel and Romney Humphries sit down with Dr. Sharmila Maneshwar and Dr. Jeff Klausner to discuss a breakthrough in HPV diagnostics: urine-based testing.

While vaccination and clinical screening have reduced cervical cancer rates, participation has stalled due to barriers like healthcare access and the invasive nature of traditional clinician-collected samples. This conversation explores how novel high-volume urine concentration technology is changing the landscape, making screening more accessible, private, and efficient.

🕒 Inside This Episode:

0:00 – Introduction: The Intersection of Innovation and Access

2:15 – The Current State of HPV: Stalled Vaccination & Screening Rates

5:30 – Breaking Down Barriers: Why Clinical Visits Can Be a Hurdle

8:00 – The Technology: How High-Volume Urine Concentration (Phasify) Works

11:45 – Clinical Study Results: Comparing Urine Testing to the Standard of Care

15:20 – Analytical Sensitivity vs. Clinical Validity

18:10 – The Future: Home Collection, STI Screening, and Oncology Biomarkers

22:00 – Final Thoughts: The Path Toward Elimination of Cervical Cancer

Guests:

Sharmila Manjeshwar, Ph.D.
Jeffrey Klausner M.D. MPH

Performance of a novel, urine-based test for the detection of cervical human papillomavirus infection: https://journals.asm.org/doi/10.1128/jcm.01318-25

This episode of Editors in Conversation is brought to you by the Journal of Clinical Microbiology and hosted by JCM Editor in Chief, Romney Humphries, Ph.D., D(ABMM) and Elitza (Elli) Theel, Ph.D., D(ABMM).

Editors in conversation is supported by the American Society for Microbiology, which publishes JCM. Become an ASM member to receive up to 50% off publishing fees when you publish in JCM or any of the ASM journals.

Sign up at https://asm.org/joinasm.

Visit https://journals.asm.org/journal/jcm to read articles and/or submit a manuscript.

This video is for informational and educational purposes only and is not medical advice. Always consult a physician or qualified health provider with questions about any medical condition.

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