विवरण
Join the Amoeba Sisters as they introduce the cardiac conduction system! This video mentions conductive cardiac cells (focusing on pacemaker cells) in the SA and AV nodes and discusses general steps of spontaneous depolarization. It also introduces essential components of the heart's conduction system including the Bundle of His (atrioventricular bundle), right and left bundle branches, and Purkinje fibers. This video assumes students have already seen the Amoeba Sisters Circulatory System video https://youtu.be/_vZ0lefPg_0?si=7fUtCnQxZDIDdFxq
TABLE OF CONTENTS:
00:00 Intro
0:56 Pulse
1:14 Reflecting on Heartbeat
1:47 Major Structures and Tissue Review
3:24 Focus on Conductive Cells in Video
3:29 SA Node with Pacemaker Cells
4:05 Membrane Potential
4:41 Funny Current (Pacemaker Current)
5:39 Threshold
5:48 Action Potential in Pacemaker Cells
6:58 AV Node
8:29 Bundle of His and Beyond
8:59 Recap
10:30 ECG (Electrocardiogram)
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Special thanks to Steven Powell, CRNA, for assisting us with script and proofing.
FACTUAL REFERENCES:
Hall, John E, and Michael E Hall. Guyton and Hall Textbook of Medical Physiology. 14th ed., S.L., Elsevier - Health Science, 2021.
Kaplan, Joel A. Kaplan’s Cardiac Anesthesia. Elsevier Health Sciences, 9 June 2023.
McCance, Kathryn, and Sue Huether. Pathophysiology: The Biologic Basis for Disease in Adults and Children. 9th ed., St. Louis, Missouri, Elsevier, 2023.
Urry, Lisa A, et al. Campbell Biology. 11th ed., New York, NY, Pearson Education, Inc, 2017.
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FURTHER READING SUGGESTIONS:
More about SA node cells appearance?
https://academic.oup.com/cardiovascres/article/47/4/658/270889
How did the "funny current" get its name?
https://pmc.ncbi.nlm.nih.gov/articles/PMC6987461/
More about HCN channels in the heart?
https://pmc.ncbi.nlm.nih.gov/articles/PMC17793/
What about other cells that are in the heart, such as cardiac fibroblasts?
https://doi.org/10.1161/jaha.120.019338
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